Messenger RNA Coding RNA Messenger RNA (mRNA) acts as the intermediate molecule between the gene and the polypeptide translation product. Its existence was postulated by Crick and his associates during the 1950s. Among the indirect evidence for mRNA at that time was the knowledge that in eukaryotes the genes reside on the chromosomes in the nucleus, whereas protein … [Read more...] about Coding And Non-Coding RNAs
Molecular Biology
Messenger RNA Questions And Answers
Messenger RNA Questions And Answers Question 1. What are intervening sequences or introns? What is mRNA splicing? Answer: Untranslated sequences that interrupt the coding sequence of a transcript and that are removed before translation begins. Removal of introns. Question 2. Many eukaryotic genes contain noncoding introns that separate the coding … [Read more...] about Messenger RNA Questions And Answers
RNA Editing Notes
RNA Editing In the late 1980s, still, another quite unexpected form of post-transcriptional RNA processing was discovered in several organisms. In this form, referred to as RNA editing, the nucleotide sequence of a pre-mRNA is changed before translation. As a result, the ribonucleotide sequence of the mature RNA differs from the sequence encoded in the exons of the DNA … [Read more...] about RNA Editing Notes
Rna Processing And Modifications Notes
Modification And Processing Of mRNA Most eukaryotic mRNAs undergo a quite complicated series of modifications and processing events before translation occurs. These include: Chemical modification to the two ends of the mRNA molecule (Capping). Polyadenylation Removal of introns (Splicing). In a few special cases, alterations to the nucleotide sequence of the mRNA … [Read more...] about Rna Processing And Modifications Notes
Translation Protein Synthesis
Translation Protein Synthesis DNA, with its correct mechanism of replication, serves to carry genetic information from cell to cell and from generation to generation. This information is translated into proteins that determine the phenotype. Virtually, all the phenotypes examined so far are the result of biochemical reactions that occur in the cell. All of these reactions … [Read more...] about Translation Protein Synthesis