Kristensmith Taylor

Diuretics Introduction Diuretics are drugs, which increase the rate of urine flow. However, clinically useful diuretics also increase the excretion of Na+ and an accompanying anion (negatively charged ion) like Cl-. Since NaCl is the major determinant of extracellular fluid volume, diuretics reduce extracellular fluid volume (decrease in edema) by decreasing total body … [Read more...] about Medicinal Chemistry of Diuretics

Antianginal Drugs Drugs Acting On the Cardiovascular System The drugs acting on the cardiovascular system are divided into four groups: Cardiotonic drugs. Anti-hypertensive drugs. Anti-arrhythmic drugs Anti-anginal drugs. Antianginal Drugs These are the drugs used in the treatment of angina pectoris. Angina pectoris, commonly known as angina, is severe chest … [Read more...] about Antianginal Drugs Classification

Antineoplastic Drugs Introduction Cancer is the rapid creation of abnormal cells that grow beyond their usual boundaries, and which can then invade adjoining parts of the body and spread to other organs. This process is referred to as metastasis. Metastases are the major cause of death from cancer. (WHO). Cancer known medically as a malignant neoplasm is a broad group … [Read more...] about Medicinal Chemistry of Antineoplastic Drugs Notes

Antihistaminic Agents Histamine Histamine or β-imidazolyl ethylamine is synthesized from L-histidine by histidine decarboxylase, an enzyme that is expressed in many mammalian tissues including gastric mucosa parietal cells, mast cells, basophils, and the central nervous system (CMS). As a result, histamine plays an important role in human physiology including regulation … [Read more...] about Medicinal Chemistry of Antihistamines Agents Notes