Systemic Antibiotics In Periodontal Therapy

Drugs Used In Periodontal Therapy

Write short note on local drug delivery system.
Or
Write short note on local drug delivery (LDD).
Or
Write short note on LDD.
Or
Write short answer on local drug delivery.
Answer. Local drug delivery systems are developed due to the limited efficacy of mouthrinsing and irrigation in deep pockets.

Main aim of the drug delivery system is to direct antimicrobials to the infection sites and maintaining effective level of drugs for sufficient period of time without producing any major side effects.

Various Local Drug Delivery Systems Used in Periodontics are:

 

Local Drug Delivery Indications

• As an adjunct in the treatment of few localized nonresponding sites in an otherwise controlled patient.
• In failing implant cases.
• In medically compromised patients in whom surgical procedures are not recommended.
• In cases with periodontal abscess.
• In cases with periodontal maintenance therapy.
• In patient with gastrointestinal intolerance to systemic drug medication.

Local Drug Delivery Contraindications

• Patients having history of allergy to any particular antimicrobial agent.
• During pregnancy and lactating periods.
• In the children under the age of 12 years.
• Subjects with complete renal failure.
• Subjects susceptible to infective endocarditis.

Local Drug Delivery Advantages

• Presence of high concentration of drug in subgingival sites.
• Patient compliance is absent.
• Does not affect symbiotic microflora of gastrointestinal tract.
• Systemic intolerance gets bypassed.

Local Drug Delivery Disadvantages

• It is difficult to place therapeutic concentrations of the antimicrobial agents in deeper areas.
• Professional application is mandatory, if used manually requires undergo dexterity and patient compliance.
• Complete drug penetration is impossible and extra pocket sites remain unaffected.

Read And Learn More: Periodontics Question And Answers