Pyogenic Granuloma

Pyogenic granuloma is considered as an exaggerated conditioned response to minor trauma.
Pyogenic granuloma is a misnomer since condition is not associated with pus formation.

Pyogenic Granuloma Etiology

It is caused by microorganisms such as streptococci and staphylococci.
If there is minor trauma to the tissue it provides the pathway for the non-specifi microorganisms which can cause pyogenic granuloma.
Hormonal imbalance can lead to pyogenic granuloma.
The sulfhdryl molecule is the agent which lead to pyogenic granuloma.

It occurs at the age of 10 to 40 years.
Female predilection is present.
Most affcted sits are lip, gingiva, tongue, palate, vestibule.
Lesion is more common in maxillary anterior region.
Lesion is elevated, pedunculated or sessile mass with a smooth, lobulated or warty surface which is ulcerated.
On manipulation, the ulcer bleeds.
Lesion is pink to red to purple in color depending on age of the lesion. It is usually painless and is soft in consistency.
Size of the lesion ranges from 1 mm to centimeters.

Overlying epithelium is thin and atrophic. At times, it is hyperplastic too.
Surface of the epithelium is usually ulcerated and is replaced by thick firinopurulent membrane.
Underlying connective tissue has number of endothelial lined vascular spaces engorged with RBCs and extreme proliferation of firoblasts and budding endothelial cells.
There is presence of moderate infitration of PMN leukocytes, lymphocytes and plasma cells.
Areas of hemorrhage and hemosiderin pigmentation is seen in connective tissue stroma.

Bacterial Infections of oral Cavity Pyogenic granuloma

Pyogenic Granuloma Treatment
Surgical excision of the lesion is done.