Nifedipine

Nifedipine

Question 1. Write On Nifedipine As Antihypertensive.
Answer:

Nifedipine is a calcium channel blocker.

• It comes under the subclass of calcium channel blockers, i.e. Dihydropyridines.
• Nifedipine is a prototype drug.

Nifedipine: Mechanism of Action, Uses, and Side Effects

Nifedipine Mechanism of Action

Nifedipine Adverse Effects

Palpitation, flushing, ankle edema, hypotension, headache, drowsiness, nausea, reflux tachycardia, fatigue, dizziness, and sedation.

Nifedipine Uses

• Nifedipine is used in the treatment of Raynaud’s disease.
• It is an alternate drug for premature labor.
• It is used as a first-line drug for hypertension.
• It is used as an antianginal drug.

Question 2. Discuss Basis Of Verapamil In Paroxysmal Supraventricular Tachycardia.
Answer:

Paroxysmal supraventricular tachycardia is a sudden atrial tachycardia.

• It is a type of arrhythmia.
• In paroxysmal supraventricular tachycardia, the atrial rate is 150–200 minutes.
• Verapamil is a calcium channel blocker and lies in class IV of antiarrhythmic drugs.

Nifedipine for Hypertension and Angina: Dosage and Efficacy

Verapamil Mechanism of Action

Verapamil increases the repolarization of the AV node and decreases SA node discharge and suppresses ectopic foci due to this it undergoes antiarrhythmic action. So that’s why Verapamil is used in paroxysmal supraventricular tachycardia.