Macrolide Antibiotics

Older macrolide: Erythromycin
Newer macrolide: Roxithromycin, clarithromycin, azithromycin.

Enumerate Macrolide Antibiotics. Describe The Important Uses And Adverse Effects Of Azithromycin.
Answer:

Enumeration Of Macrolide Antibiotics

Uses Of Azithromycin

Macrolide Antibiotics: Mechanism of Action and Uses

Legionnaires pneumonia: Azithromycin should be given 500 mg OD oral/IV for two weeks.
Chlamydia trachomatis: In this, there is non-specific urethritis and genital infections are present in both men and women. A 1 gm single dose of azithromycin is curative. It is also the drug of choice for chlamydial pneumonia.
Donovanosis: It is treated with azithromycin 500 mg OD for 7 days.
Chancroid and PPNG urethritis: Single 1 gm dose is highly curative.
It is also used to cure pharyngitis, tonsillitis, sinusitis, otitis media, pneumonia, acute exacerbation of chronic bronchitis, streptococcal, and some staphylococcal skin and soft tissue infections.
Prophylactic use: Azithromycin is given before surgical procedures to prevent bacterial endocarditis in patients with valvular lesions. It is also used for prophylaxis of recurrence in rheumatic fever.

Azithromycin Adverse Effects

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