Histopathology Of Intraepithelial Carcinom
This is also called as carcinoma in situ
- Intraepithelial carcinoma is a condition which arises frequently on skin, but occurs also on mucus membrane including those of oral cavity.
- Metastasis is impossible in intra epithelial carcinoma.
- Bowen’s disease is a special form of intraepithelial carcinoma occurring with some frequency on skin, particularly in patients who have had arsenic
therapy and is often associated with development of internal or extra cutaneous cancer.
“Importance Of Studying Histopathology In Intraepithelial Carcinoma”
Histopathology Of Intraepithelial Carcinom Histological Features
- Keratin may or may not be found on the surface of lesion but, if present, is more apt to be parakeratin rather than orthokeratin.
“Risk Factors For Developing Intraepithelial Carcinoma”
- In some instances, there appears to be hyperplasia of the altered epithelium while in others there is atrophy.
- An increased nuclear/cytoplasmic ratio and nuclear hyperchromatism is seen.
“Understanding The Role Of Dysplastic Cells In Intraepithelial Carcinoma Histopathology”
- Cellular pleomorphism is common
- There is loss of orientation of cells and loss of their normal polarity.
- Sometimes a sharp line of division between normal or altered epithelium extends from surface down to the connective tissue rather then a blending of epithelial changes.
Histopathology Of Intraepithelial Carcinom Treatment
- Treatment is done by surgery, radiotherapy or electrocautery
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