Hashimoto’s Disease
Write short note on hashimoto disease of thyroid.
Answer. It is an autoimmune disease
It is also called as Hashimoto’s thyroiditis or diffuse non-goitrous thyroiditis or struma lymphomatosis.
“The Role Of Blood Tests In Monitoring Hashimoto’S Disease”
Hashimoto’s thyroiditis Clinical Features
- It is very common in women. Most common in perimenopausal females.
- There is painful, diffuse enlargement of both the lobes of thyroid gland which is fim, rubbery, tender and smooth.
- Initially, both lobes ofthyroid are present with toxic features butlater they manifest with the features of hypothyroidism.
- Hepatosplenomegaly can be present.
- The condition can predispose to papillary carcinoma of thyroid.
“Causes Of Graves’ Disease In Adults”
Hashimoto’s thyroiditis Histology
- Histology is characterized by extensive lymphocytic infitration resulting in destruction of thyroid follicles with
variable degree of firosis. - The thyroid follicles are destroyed by signifiant firosis.
- The deep eosinophilic staining thyroid follicular cell
Askanazy cell, is characteristic.
“Natural Remedies For Hashimoto’S Disease”
Hashimoto’s Thyroiditis Investigations
- FNAC can be done
- Assessment of T3, T4 and TSH levels
- Thyroid antibodies assay: Signifiant rise is observed in 85% of cases.
- ESR is very high, i.e. over 90 mm/hour.
“Early Signs Of Hashimoto’S Disease Progression”
Hashimoto’s thyroiditis Treatment
- L-thyroxine 0.2 mg/day is given as a supplementary dose.
- lf there is compression on the trachea, isthmusectomy is done to relieve compression.
- lf the goitre is big and causing discomfort, subtotal thyroidectomy can also be done.
- Steroid therapy often is helpful.
Complications of Hashimoto’s thyroiditis
- Permanent hypothyroidism
- Papillary carcinoma of the thyroid
- Malignant lymphoma.
Leave a Reply