Classification Of Antifungal Drugs

Classification Of Antifungal Drugs

Classify Antifungal Drugs. Discuss Nystatin In Detail With A Note On Its Use In Dentistry.
Answer:

Classifiation Of Antifungal Drugs

• Antibiotics
  • Polyenes: Amphotericin B, nystatin, natamycin
  • Heterocyclic benzofuran: Griseofulvin
• Antimetabolite: Flucytosine
• Azoles
  • Imidazoles: Clotrimazole, meconazole, oxiconazole
  • Triazoles: Fluconazole, itraconazole
• Allylamine: Terbinafi
• Other topical agents: Benzoic acid, sodium thiosulphate, butenafine.

Antifungal Drugs: Classification and Types (Systemic and Topical)

Nystatin

• It is an antifungal drug.
• It is a polyene antifungal antibiotic.
• It is obtained from Streptomyces noursei.

Nystatin Mechanism Of Action

Nystatin Therapeutic Uses

• It is used topically in oral candidiasis, corneal candidiasis, conjunctival candidiasis, and cutaneous candidiasis.
• Nystatin tablets should be taken for intestinal candidiasis, superinfection due to candidiasis, and in Mongolia diarrhea.
• Nystatin vaginal suppositories are used in vaginal candidiasis.
• Nystatin is also used in the treatment of angular cheilitis and antibiotic-associated stomatitis.

Classification of Antifungal Drugs: Types and Mechanism of Action

Nystatin Side Effects

Nausea and bad taste.

Nystatin In Dentistry

• Topical nystatin remains a drug of choice for the treatment of candidal infections of the oral cavity.
• For oral candidiasis one lozenge, i.e. 200,000 units may be used 4 to 6 times per day.
• For denture stomatitis nystatin as an ointment can be applied topically every 6 hours to the tissue surface of the denture.
• Nystatin is also used in the treatment of angular cheilitis and antibiotic-associated stomatitis.