Anticancer Drugs Question And Answers

Anticancer Drugs Question And Answers

Question 1. Write A Short Note On The Toxicity Of Methotrexate.
Answer:

“Complications of ignoring cancer progression”

Methotrexate is a folate antagonist.

• The toxicity of methotrexate is caused due to overdosages.
• Aspirin and sulphonamides increase the toxicity of methotrexate by decreasing its renal tubular excretion.
• Folinic acid rapidly reverses the toxicity of methotrexate. The folinic acid gets converted to a form of tetrahydrofolate which is utilized by the cells.
• Thymidine also counteracts methotrexate toxicity.

“Importance of studying anticancer drugs for healthcare professionals”

“Techniques for managing high-risk groups with cancer”