Burkitt Lymphoma

Burkitt Lymphoma

• Endemic (African): Occurs commonly in jaw.
• Non-endemic (Sporadic): Occurs commonly in abdomen
• Aggressive lymphoma: In HIV patients.

• It is commonly seen in children during the age of 6–9 years.
• Males are commonly affcted as compared to females.
• Male to female ration is 2:1.
• Lesion is found most commonly in maxilla and spreads towards flor of the orbit.
• In African form jaw is more involved while in American form abdominal involvement is common.
• Lesion has very fast growth and it doubles in size within a day.

“Symptoms Of Burkitt Lymphoma”

• Patient complaints swelling of jaw, abdomen and paraplegia.
• Peripheral lymphadenopathy is commonly seen.
• Renal involvement is present which can be bilateral.
• In females, ovaries are also affcted.

B-Cell Burkitt Lymphoma

“Signs Of Burkitt Lymphoma In Adults”

• Tumor is rapidly growing and involves maxillary, ethmoidal and sphenoidal sinus along with orbit.
• Presence of loosening and mobility of permanent teeth.
• Presence ofparesthesia ofinferior alveolar canals and other sensory facial nerves.
• Gingiva adjacent to affcted teeth become swollen, ulcer ated and necrotic.
• There can be presence of large amount of mass in the mouth on the surface of which present the rootless developing permanent teeth.

High-Grade B-Cell Lymphoma – Burkitt Type

• Radiograph: It shows moth-eaten appearance with loss of lamina dura.
• Biopsy: Starry Sky appearance is characteristic for Burkitts lymphoma.
• USG: This done for abdomen so that kidneys should be evaluated.
• Blood urea and serum creatinine estimation is done.

• Radiotherapy.
• Chemotherapy, i.e. cyclophosphamide, methotrexate,orthomelphalan.
• Surgery is usually not indicated unless it is localized or in case of involvement of ovaries.