White Blood Cell

White Blood Cell

Classify WBCs and describe their function with diagrams.
Answer:

WBC [White Blood Corpulscles]:

• Synoym – leukocytes.
  • They are the colorless and nucleated formed elements of blood.
  • They play an important role in defense mechanism.

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White Blood Corpulscles Classification:

• WBC are classified on the basis on the presence or absence of granules in the cytoplasm.
  1. Granulocytes – with granules
     • Neutrophils
     • Eosinophils
     • Basophils.
  2. Agranulocytes – without granules.
     • Monocytes.
     • Lymphocytes.

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White Blood Corpulscles Neutrophils 60-70%:

• Size-10-12 μ diameter
• Nucleus is multilobed [2-5 lobes].
• Young nucleus have single “horse shoe shape’ nucleus.
• Cytoplasm contains fine granules containing many enzymes like myeloperoxidase and proteases.

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White Blood Corpulscles Eosinophils – 2-5%:

• Size-10-14 μ diameter.
• Nucleus is bilobed.
• Cytoplasm is granular, acidophilic.
• Granules contains peroxidise and lysozomes.

White Blood Corpulscles Basophils 0-1%:

• Basophils Size: 8-10 m diameter
• Nucleus is bilobed.
• Cytoplams contains basophilic coarse granules.

White Blood Corpulscles Monocytes: 3-8%:

• Nucleus is round, oval, horse shoe or kidney shaped.
• Monocytes Size: largest, 14-18 μ diameter.
• Cytoplasm is clear.

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White Blood Corpulscles Lymphocytes – 20-30%:

Lymphocytes Size:

1. Large lymphocytes – 10-12 μ diameter and
2. Small lymphocytes-7-10 μ diameter.
   • Nucleus is large, oval or kidney shaped.
   • Functional types are
     1. T lymphocytes
     2. B lymphocytes.

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