Uses And Adverse Effects Of Adrenaline

“What are the uses and adverse effects of adrenaline?”

Therapeutic Uses Of Adrenaline

Anaphylactic shock: Adrenaline acts as a life-saving drug in anaphylactic shock and also in Type I hypersensitivity reaction. It should be given as 0.3 to 0.5 ml of 1:1000 solution and is given IM.
Allergy: It reverses the manifestations of allergic disorders.
Adrenaline along with the lignocaine due to its vasoconstrictor effect causes late absorption of local anesthetic and prolongs the duration of local anesthesia.

“Impact of adrenaline in managing cardiac arrest”

Bronchial asthma: Adrenaline acts as a powerful bronchodilator in bronchial asthma. It is very useful during acute attacks. It should be given 0.3 to 0.5 ml of 1:1000 solution SC
Hemostatic: Adrenaline acts as a local hemostatic for the control of bleeding from tooth extraction and also in various other surgical procedures.
Cardiac arrest: Adrenaline is used in the treatment of cardiac arrest which happens due to drowning or electrocution. Adrenaline is given IV in 1:10000 concentration with other supportive measures.
Glaucoma: Adrenaline is used in glaucoma as it shows poor penetration when it is applied locally in the eye, so it should be given as a prodrug.

“Importance of monitoring adrenaline side effects in treatment”

Adverse Effects Of Adrenaline

On SC or IM administration it causes transient restlessness palpitation, anxiety, headache, pallor, and tremors.
On IV administration it causes the following adverse effects, i.e.
- Cerebral hemorrhage
- Sudden rise in blood pressure
- Ventricular tachycardia/fibrillation
- Angina
- Myocardial infarction.

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