Unstable Angina Treatment And Management
Question. Write the management of unstable angina pectoris.
Or
Write the management of unstable angina.
Answer.
1. To control acute disease and stabilize the thrombotic process:
“Importance of studying unstable angina for healthcare professionals: Questions explained”
- Hospitalization – to facilitate rapid adjustments in therapy, which are usually required.
- Oxygen administration and sedation.
- Therapy with beta blockers and calcium antagonists.
- Sublingual nitrates for immediate relief.
- IV nitrates – IV Nitroglycerin 3-10 µg / min if the patient does not settle on the above therapy. IV nitrates produce hypotension, and regular BP measurements are required, and the dose is increased.
- Aspirin 325 mg. OD and Clopidogrel 75 mg / day or Prasugrel 10 mg / day.
- Anticoagulation with heparin. Dose 60 U / kg IV bolus followed by 12 U / kg / hr infusion. Low molecular heparin is superior to unfractionated heparin in the dose of 1 mg / kg 12 hourly subcutaneous.
- Glycoprotein IIb / IIIa receptor inhibitors, which block the receptors that lead to platelet aggregation
“Understanding unstable angina through FAQs: Treatment and management explained”
- Eptifiatide 180 µg / kg IV bolus followed by 2 µg / kg / min. infusion.
- Tirofian 0.4 pg / kg / min over 30 mins, followed by 0.1 µg / min. infusion.
- Abciximab 0.25 mg / kg IV bolus followed by 0.125 µg / kg / min. infusion.
2. Long-term management of underlying coronary artery disease, with revascularization procedures.
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