Understanding Muscle Proteins And Their Role In Movement

Understanding Muscle Proteins And Their Role In Movement

Question 1. Name the muscle proteins
Answer:

1. Myosin molecule

• Forms myosin filament
• It is globulin polypeptide containing 2 heavy chains and 4 light chains
• These chains twist around each other

2. Actin molecule

• Forms actin filament
• Its active site gives attachment to myosin molecule

3. Tropomyosin

• Present in actin filament
• In relaxed state, covers all active sites of actin filament

4. Troponin

• Present in actin filament
• Subunits:
  • Troponin I-attached to F actin
  • Troponin T-attached to tropomyosin
  • Troponin C-attached to calcium ions

Question 2. Mention the neurotransmitter that is secreted at the neuromuscular junction and what is myasthenia gravis.
Answer:

• Acetylcholine is the neurotransmitter that is secreted at the neuromuscular junction.

Myasthenia gravis:

• It is a neuromuscular disease characterized by grave weakness of the muscle.

Myasthenia gravis Symptoms:

• Muscles mostly involved are facial, extra ocular, swallowing and masticatory muscles.
• Rapid onset of fatigue
• Slow and weak muscular contraction
• Marked generalized weakness of muscles