Transamination Reactions And Its Features

Transamination Reactions And Their Features

Transamination reactions.
Answer.

Transamination Definition

Transamination is a reaction in which the amino group of one amino acid is transferred to a keto acid, resulting in the formation of a new amino acid and a new keto acid

Transamination Reactions: Mechanism and Features

Urea Cycle: Mechanism and Key Steps

Characteristic Features

• Transamination is a reversible reaction
• It takes place in the liver, kidneys, heart, and brain
• The enzyme required is called transaminase

Transamination Reactions in Amino Acid Metabolism

The Urea Cycle: Role in Detoxification and Nitrogen Excretion 

• Pyridoxine is required as a coenzyme for the reaction
• While most amino acids can act as donors, the recipient keto acids may be alpha-ketoglutarate, oxaloacetate or pyruvate
• All the recipient keto acids are components of the Krebs cycle
• The amino acids which do not take part in transamination are lysine, threonine, proline, and hydroxyproline