Structure and Function of the Cell Membrane: Fluid Mosaic Model Explained
Question 1. Describe the fluid mosaic structure of the cell membrane.
Answer.
Structure Of Cell Membrane/Fluid Mosaic Model Of Cell Membrane Membrane
- The fluid mosaic model proposed by Singer and Nicholson (1972) is the most acceptable model for membrane structure
- The membranes are composed of lipids, carbohydrates, and proteins
- The actual composition differs from tissue to tissue
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- Among the lipids, amphipathic lipids (containing hydrophobic and hydrophilic groups), namely phospholipids, glycolipids, and cholesterol, are found in the membrane
- The biological membranes have a thickness of 5 to 8 nm
- A membrane is essentially composed of a lipid bilayer
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- Membrane proteins are categorized into 2 groups
- Extrinsic proteins – these are peripheral membrane proteins which are loosely held to the surface of the membrane and they can be easily separated eg, Cytochrome C of the mitochondria
- Intrinsic proteins – these are integral proteins which are tightly bound to the lipid bilayer and can be separated only by the use of detergents or organic solvents eg, hormone receptors and cytochrome
Fluid mosaic model of the cell membrane
- The membrane is asymmetric due to the irregular distribution of proteins
- The lipid and protein subunits of the membrane give an appearance of mosaic or ceramic tile
- Unlike a fixed ceramic tile, the membrane changes; hence, the structure of the membrane is considered as fluid mosaic
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Fluid Mosaic Model

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Question 2. Functions Of the Cell Membrane.
Answer.
Functions Of the Cell Membrane:
- It separates and protects the cell from the external hostile environment
- The plasma membrane provides a connecting system between the cell and its environment
- It acts as a semi-permeable membrane
- Absorptive function
- Excretory function
- Exchange of gases
- Maintenance of the size and shape of the cell.
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