Radiation Hazards

Radiation Hazards

What are hazards of radiations? discuss how to get protection from the same.
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Describe radiation protection measures.
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Discuss in detail about various radiation protection measures.
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Write in detail about radiation hazards.
Answer.

Hazards of Radiation

Radiation hazard on skin

The reaction of the skin to radiation may be categorized as:

• Early or acute signs:
  • Increased susceptibility to chapping.
  • Intolerance to surgical scrub.
  • Blunting and leveling of finger ridges.
  • Brittleness and ridging of finger nails.
• Late or chronic signs:
  • Loosening of hair and epilation.
  • Dryness and atrophy of skin, due to destruction of the sweat glands.
  • Progressive pigmentation, telangiectasis and keratosis.
  • Indolent type of ulcerations.
  • Possibility of malignant changes in tissue.

Radiation hazard on Eyes

• Epilation of eyelashes.
• Inflammation, fibrosis and decreased flexibility of the eyelid.
• Damage to the lacrimal glands, leading to dryness.
• Ulceration of the cornea.
• Initiation of cataract formation from the periphery towards the center.

Radiation hazard on Ears

• Columnar epithelium of the middle ear may be desquamated.
• Edema of the mucosa and collection of sterile fluid in the middle ear, which leads to obstruction of the eustachian tube known as radiation otitis media.
• Deafness due to rupture of eardrums.

Radiation hazard on Reproductive system

• On Testicles:
  • Suppression of germinal activity.
  • Alteration in fertility.
  • Functional changes in the offspring may be seen.
• On Ovary:
  • The various cells respond differently to irradiation.
  • Increase in frequency of hemangioma in children receiving dose of radiation in utero.

Radiation hazard in oral cavity

Oral Mucosa

• Oral mucous membrane contains the basal layer of differentiating inter-mitotic cells which are highly radiosensitive at the end of second week of therapy the mucous membrane begins to show areas of redness and inflammation, this state is called as “Mucositis.”
• As the therapy continues the mucous membrane breaks down with the formation of white or yellow pseudomembrane.
• At the end of therapy the mucositis is severe, painful leading to difficulty in talking, eating and swallowing.
• After termination of therapy, the healing may be complete after about two months, but the mucous membrane tends to become thin, atrophic and relatively avascular. Secondary infection by candida albicans is very common complication.
• Patient is usually prone to oral ulcerations and unable to tolerate dentures.

Effects on Taste Buds

• Taste buds are sensitive to radiation even therapeutic dose of radiation causes degeneration of taste buds.
• Loss of taste sensation occurs during 2nd and 3rd week of therapy.
• Loss of taste sensation can be partial or complete.
• Posterior two-third of the tongue when irradiated effects the bitter and acid flavors.
• Anterior one-third of the tongue when irradiated effects sweet and salty flavors.

Effects on Salivary Glands

• Parenchymal component of the gland is sensitive to radiation.
• Glands demonstrate progressive fibrosis, adiposis, loss of fine vasculature.
• There is marked decrease in salivary flow.
• The composition of saliva is affected.
• There is increased concentration of sodium, chloride, calcium, magnesium ions and proteins.
• Saliva losses its lubricating properties.
• Mouth becomes dry and tender due to xerostomia.
• pH of saliva is decreased which may initiate decalcification of enamel.

Effects on Teeth

Adult teeth are resistant to the effects of radiation.

Radiation Caries

• Involve mainly cementum and dentin at cervical lesion.
• Dark pigmentation of crown.
• Superficial lesion affects buccal, incisal, palatal and occlusal surfaces.

During Development

• Before calcification: There is complete destruction of tooth bud which results in partial anodontia.
• Once calcification starts: Hypoplastic changes seen.
• During root development: Retardation or loss of root development.

After Eruption

Radiation caries: It is a form of rampant caries; it is secondary to the change in saliva.

Effects on Bone

• Marrow is replaced by bone marrow and fibrous connective tissue.
• Endosteum becomes atrophic.
• Bone becomes hypovascular hypocellular and hypomineralized.
• The complication following irradiation, i.e. “osteoradionecrosis”.
• Necrosis of bone may result in nonhealing ulcer which may occur after tooth extraction.
• Lack of osteoblastic and osteoclastic activity in endosteum.
• Mandible affects more than maxilla.

Acute Radiation syndrome

When the whole body is exposed to low or moderate doses of radiation, a very characteristic change are seen known as acute radiation syndrome. This can be followed by death within a month. If an individual survive, it can show late somatic changes which are:

• Prodromal syndrome (1 to 2 Gy): Shortly after exposure patient may develop nausea, vomiting, diarrhea and anorexia.
• Latent period: It is a period of apparent well being, the extent of which is dose related. Symptoms follow the latent period when the individuals are exposed in the lethal range (approximately 2–5 Gy) or the supralethal range (more than 5 Gy).
• Bone marrow (hemopoietic) syndrome {2 to 7 Gy): Here severe damage may be caused to the circulatory system. The bone marrow being radiosensitive, results in fall in the number of granulocytes, platelets and erythrocytes. Clinically, this is manifested as lymphopenia, granulocytopenia and or hemorrhage due to thrombocytopenia and anemia due to depletion of the erythrocytes.
• Gastrointestinal syndrome (7 to 15 Gy): This causes extensive damage to the gastrointestinal tract, leading to anorexia, nausea, vomiting, severe diarrhea and malaise. Injury to the basal cell epithelial cells of the intestines causes denuded mucosal surfaces, leading to loss of plasma and electrolytes, hemorrhage and ulcerations leading to diarrhea, dehydration and loss of weight. Finally, leading to septicemia unusually leading to death.
• Cardiovascular and central nervous system syndrome (more than 50 Gy): This produces death within one or two days. Individuals show intermittent stupor, incoordination, disorientation and convulsions suggestive of extensive damage to the nervous system.

Protection from hazards of Radiation

Protection of Patient

• X-ray machine: Good machines of reputed companies should be used.
• Selection of film: F- and E-speed films are used as they are of good quality and are highly sensitive. E speed films or Ekta speed films reduce exposure to 40%.
• Focal spot film distance: Longer is the focal spot film distance decrease is in the exposed tissue volume.
• Source skin distance: Increase in the source skin distance reduces the size of beam and reduces the volume of tissue irradiation which decreases the patient dose.
• Filtration: Low energy X-ray beam is removed by the filtration. As these X-rays do not contribute to the image formation they should be removed before they reach to the patient as they lead to the radiation exposure.
• X-ray collimation: It prevent the scattering. Beam should be collimated so that it is not more than 7 cm in diameter at the face of patient. Rectangular collimators should be preferred as they reduce the amount of tissue radiation.
• Intensifying screen: Use of rare earth screen decreases dosage for extraoral films.
• Grid: Grid decreases the fogginess of film due to the secondary radiation, this reduces the need for repeating the film.
• Kilovoltage: Operation of X-ray unit should be done at 60 to 90 kVp. X-ray beam of low kilovoltage leads to the higher patient doses, mainly to skin.
• Position-indicating devices: A 12 to 16 inches long position indicating device reduces exposure to patient as compared to short position indicating device. Open ended, circular or rectangular lead-lined cylinders are preferred to direct the X-ray beam.
• Lead aprons should be used who have lead content equivalent to 0.25 mm aluminum which is to be worn by patient during taking the radiograph.
• Thyroid collars should be weared to protect thyroid gland from radiation.
• Film-holding devices: They stabilize the X-ray film in mouth and so the hands of patient are not exposed to radiation.
• RVG: It decreases the dose of radiation required in IOPA.

Protection of the operator

• Operator should not hold X-ray film in mouth of patient at the time of exposure.
• Operator should not stabilize the X-ray machine at the time of exposure.
• Operator should not stand in the path of primary radiation.
• Operator should have to stand behind a lead barrier which consists of 0.5 mm lead equivalent during the exposure.
• Operator should stand 6 feet away from primary X-ray beam.
• Operator should have radiation exposure monitored by personal monitoring devices or film badges.
• Operator should work on the rotation of duties, to avoid accidental exposure.
• The maximum permissible dose for whole body exposure per year for occupationally exposed individual is 5 rem. It should be noted that operator should not go above the range of maximum permissible dose.

Protection of other Persons

• Persons who are needed should stay in the room.
• Conch shell design of operatory area is recommended for protection of people in the surrounding areas.
• X-ray tube is away from doorways to avoid the accidental exposure.
• Monitoring of the radiation exposure to room and adjacent office premises is done.
• Walls of X-ray shooting room consists of either the barium plaster or the increased thick walls which consists of additional layer of bricks.
• Displaying of warning signs and caution should be done.
• Regular radiation surveys should be carried out at regular intervals to detect the amount of radiation exposure