Pathogenesis Of Recurrence In Odontogenic Keratocyst

Pathogenesis Of Recurrence In Odontogenic Keratocyst

Question. Describe in brief reasons for recurrence of odontogenic keratocyst.

“Importance of studying recurrence in odontogenic keratocysts for better outcomes: Questions explained”

Answer. Following are the reasons for recurrence of odontogenic keratocyst:

• Odontogenic keratocyst multiply in some patients including the occurrence of satellite cysts which may be retained during an enucleation procedure.
  If enucleation procedures are incomplete may be new cyst arise from retained satellite microcysts or retained mural cell islands.
• Linings of odontogenic keratocyst are thin and fragile and are diffilt to enucleate. Portions of lining may remain left behind and lead to recurrence.

“Understanding the pathogenesis of recurrence in OKC: Q&A explained”

• When OKC is enucleated in a single piece chances of recurrence are low while when it is removed in multiple pieces chances of recurrence is high.
  This is because in multiple pieces at times remnants of cyst remain which lead to recurrence.
• OKCs may also arise from proliferation of basal cells of oral mucosa also known as basal cell hamartias in third molar region and ascending ramus of mandible.
  It was observed that there is perforation of overlying bone and firm adhesion of cyst to overlying mucosa.
  So when cysts were surgically removed overlying mucosa should be excised with them to prevent recurrence from residual basal cell proliferations. If overlying mucosa is not excised or it remains it leads to recurrence.