Oxidative And Non-Oxidative Deamination

Oxidative And Non-Oxidative Deamination

Define oxidative and non- oxidative deamination.
Answer.

Deamination Definition

The removal of amino group from the amino acid is known as deamination

Types Of Deamination

It can be of two types

• Oxidative deamination
• Non oxidative deamination

Oxidative Deamination

• It is a process in which ammonia is removed from the amino acid
• It takes place in the liver and kidney
• The enzyme required is amino acid oxidase
• Amino acid is converted to imino acid which then forms keto acid and ammonia is eliminated
• Hydrogen peroxide is formed, which is toxic to the cells and is immediately broken down by the enzyme catalase
• It does not play a major role in the formation of ammonia.

Non Oxidative Deamination

• Certain amino acids can be non-oxidatively deaminated by specific enzymes to form ammonia
• It does not play a major role in ammonia formation.