Osteoblast

Osteoblast

“How do osteoblasts contribute to bone formation? FAQ answered”

Question 1. Osteoblast
Answer:

• Cuboidal cell
• Contains
• Rough endoplasmic reticulum
• Large Golgi apparatus
• Secretory vesicles

Functions:

• Synthesizes osteoid and collagen
• Regulates mineralization

“Importance of studying osteoblasts for medical students: Questions explained”

Precursor:

• Progenitor cells

Question 2. Calcium.
Answer:

Sources of calcium:

• Milk & milk products are regarded as the best sources of calcium

Other good sources of calcium are:

• Beans, leafy vegetables, fish, cabbage, egg yolk.

Functions of calcium:

1. Development of bone & teeth
   • Calcium is required for the formation of hydroxyapatite
   • Bones serve as a reservoir of calcium
2. Muscle contraction
   • Calcium ions react with troponin C & trigger muscle contraction
   • Activates ATPase
   • Increases interaction between actin & myosin
3. Blood coagulation
   • Calcium is coagulation factor IV
4. Nerve transmission
   • It is involved in the transmission of nerve impulse
5. Membrane integrity & permeability
   • It influences the membrane structure
6. Activation of enzymes
   • It activates ATPase, lipase & succinate dehydrogenase
7. Binds with calmodulin to activate certain enzymes
8. It acts as a second messenger for certain hormonal actions
   • Causes release of insulin, PTH, calcitonin
   • Involved in endocytosis, exocytosis & cell motility
   • Involved in cell contact & cell adhesion
   • Acts on the myocardium & prolongs systole

“Common challenges in mastering osteoblast notes effectively: FAQs provided”

Question 3. Normal serum calcium level
Answer:

Normal Serum Levels:

• Calcium-9-11 mg/dl