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Home » Mixed Radiolucent Radiopaque Lesions Of Oral Cavity

Mixed Radiolucent Radiopaque Lesions Of Oral Cavity

February 9, 2026 by Kristensmith Taylor Leave a Comment

Mixed Radiolucent Radiopaque Lesions Of Oral Cavity

Give differential diagnosis of mixed radiopaque and radiolucent lesions of jaws.
Answer.

Mixed Radiopaque and Radiolucent Lesions of Jaws

  • Intermediate stage of Paget’s disease
  • Fibrous dysplasia
  • Osteoid osteoma
  • Chronic osteomyelitis
  • Osteoradionecrosis
  • Cemento-ssifying firoma
  • Calcified epithelial odontogenic tumor (CEOT)
  • Osteogenic sarcoma
  • Chondroma
  • Chondrosarcoma
  • Central hemangioma
  • Ossifying subperiosteal hematoma

Mixed Radio-paque and Radiolucent Lesions Associated with teeth

cemento-ossifying Fibroma

  • Osteoblastoma: Histology helps in establishing diagnosis.
  • Osteosarcoma: Osteosarcoma is a malignant tumor which shows malignant characteristics such as invasion of tumor cells in sof tissue, destruction of cortices while cemento ossifying firoma is benign in nature.
  • Osteoid osteoma: More common in men at 3rd to 4th decade while cemento-ossifying firoma is common in women of same age group. Osteoid osteoma leads to pain during night while cemento-ossifying firoma is asymptomatic.
  • Calcifying epithelial odontogenic tumor (CEOT): Most common site of occurrence is posterior body and ramus of mandible while most common site of occurrence for cemento-ssifying firoma is mandibular premolar-molar region.
  • Chondrosarcoma: In chondrosarcoma borders are ill defied with formation of periosteal bone while in cemento ossifying firoma borders are well defied.
  • Periapical cemental dysplasia: In periapical cemental dysplasia occurance is in older age group as compared to periapical cemental dysplasia. Periapical cemental dysplasia occur in mandibular incisor lesion while cemento ossifying firoma occur in premolar-molar region.
  • Fibrous dysplasia: It has equal sex predilection while cemento ossifying firoma is more common in females. Border of lesion in firous dysplasia is ill-defied while in Paget’s disease borders are well defied.
  • Paget’s disease: Paget’s disease show cottn-wool appearance while no such appearance is seen in cemento-ossifying firoma.
  • Benign cementoblastoma: In benign cementoblastoma tumor is attched to the root and shows root resorption while in cemento-ossifying firoma, tumor is not attched to root. Benign cemento blastoma is associated with pain while cemento-ossifying firoma is asymptomatic.
  • Juvenile ossifying firoma: Juvenile ossifying firoma is seen in 1st to 2nd decades while cemento-ossifying firoma is seen in 3rd to 4th decades. In juvenile-ossifying firoma maxilla is commonly affected while in cemento-ossifying firoma mandible is commonly affected. Radiographic appearance of both lesions is similar, diagnosis is made histologically.

Fibrous dysplasia

  • Osteoblastic metastatic carcinoma: Osteoblastic carcinoma does not reveal monotonous pattern while fibrous dysplasia show monotonous pattrn.
  • Osteosarcoma: Osteosarcoma shows Codman’s triangle, sunburst pattrn while firous dysplasia shows granular pattern.
  • Chondrosarcoma: Chondrosarcoma is painful while in firous dysplasia, frank pain is there. Fibrous dysplasia is seen in younger age group while chondrosarcoma is seen in older age group.
  • Cemento-ossifying fibroma:
    • Cemento-ossifying fibroma has predilection for mandible while fibrous dysplasia has predilection for maxilla.
    • Shape of cemento-ossifying fibroma is rounded while of fibrous dysplasia is rectangular.
    • Margins in cemento-ossifying fibroma are sharply defied while in fibrous dysplasia, they are indistinct.
    • Cemento-ossifying fibroma is seen in young people while fibrous dysplasia is seen in older persons.
  • Paget’s disease: Serum alkaline levels are raised in paget’s disease, while they are within normal range in fibrous dysplasia.

Paget’s disease

  • Osteoblastic metastatic carcinoma: Osteoblastic metastatic carcinoma shows history of primary tumor while Paget’s disease does not had such history.
  • Osteosarcoma: Osteosarcoma occurs in younger age group while Paget’s disease occur in middle age group. Osteosarcoma shows radiographic appearance such as sun ray appearance and codman’s triangle.
  • Chondrosarcoma: One of the common symptom of chondrosarcoma is pain while pain is absent in Paget’s disease.
  • Cemento-ossifying-fibroma: Cemento-ossifying fibroma occurs in younger age group while paget’s disease occur in 40 years of age. Cemento-ossifying firoma show well defined margins while Paget’s disease shows diffuse margins.
  • Fibrous dysplasia: Fibrous dysplasia occurs in younger age group while Paget’s disease is seen during 40 years of age. Paget’s disease resemble cottn wool-appearance while firous dysplasia shows motted appearance. In firous dysplasia, maxillary sinus is reduced while in paget’s disease air space is not reduced.
  • Ossifying subperiosteal hematoma: Ossifying subperiosteal hematoma is seen in younger age, i.e. 15 years and there is also history of recent trauma.

Osteosarcoma

  • Metastatic carcinoma: In metastatic carcinoma, history of primary tumor is evident while no such history is seen in osteosarcoma.
  • Chondrosarcoma: Chondrosarcoma occurs in older age group and there is predilection for maxilla while osteosarcoma occur in middle age group and predilection for maxilla and mandible is equal.
  • Ossifying firoma: Internal structure is uniform in ossifying firoma, while it is non-uniform in osteosarcoma.
  • Fibrous dysplasia: Lesions are more demarcated and have uniform appearance as compared to osteosarcoma.
  • Ossifying subperiosteal hematoma: Patient will give history of recent trauma in ossifying subperiosteal hematoma, while it is not so in osteosarcoma.

Chondrosarcoma

  • Osteosarcoma: Chondrosarcomareveals typicalcalcifiations in radiograph which are absent in osteosarcoma.
  • Fibrous dysplasia: In radiograph, periphery of fibrous dysplasia is well defied as compared to chondrosarcoma. In chondrosarcoma, widening of PDL space is seen while in firous dysplasia thinning of PDL is seen.

Osteoid osteoma

  • Osteoblastoma: Osteoid osteoma is more painful as compared to osteoblastoma.
  • Ossifying firoma: In ossifying firoma, root resorption is present while in ossifying firoma root resorption is absent.
  • Fibrous dysplasia: In firous dysplasia, predilected site is maxilla while in osteoid osteoma slight predilection of mandible is present.

Filed Under: Oral Radiology

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