Keloid – Symptoms And Causes

Keloid – Symptoms And Causes

• In keloid, there is defect in maturation and stabilization of collagen firils. Normal collagen bundles are absent.
• Keloid is common in blacks.
• It is more common in females.
• It is genetically predisposed, often familial and is very rare in Caucasi
• Keloid continues to grow even after 6 months, may be for many years.
• It extends into adjacent normal skin. It is brownish black/pinkish black (due to vascularity) in color, painful, tender and sometimes hyperaesthetic; spreads and causes itching.

“Factors influencing success with keloid knowledge: Q&A”

• Keloid may be associated with Ehlers-Danlos syndrome or scleroderma.
• When keloid occurs following an unnoticed trauma without scar formation is called as spontaneous keloid, commonly seen in Negroes.
• Some keloids occasionally become non-progressive after initial growth.
• Pathologically, keloid contains proliferating immature firoblasts, proliferating immature blood vessels and type III thick collagen stroma.
• Keloid is common over the sternum. Other sites are upper arm, chest wall, lower neck in front.

“Understanding keloids through FAQs: Symptoms, causes, and treatments explained”

• Negro race
• Tuberculosis patient
• Vaccination site.

• Ulceration
• Infection.

“Importance of studying keloids for medical professionals: Questions explained”

• Steroid injection: Intrakeloidal triamcinolone, is injected at regular intervals, may be once in 7–10 days, of 6—8 injections.
  Its sequence is Steroid injection—excision—steroid injection.
• Methotrexate and vitamin A therapy into the keloid.
• Compressive dressings with silicone gel sheets reduce the tendency of keloid to recurr.
• Laser therapy can be given.
• Vitamin E/palm oil massage.
• Intralesional excision retaining the scar margin may prevent recurrence. It is ideal and bettr than just excision.
• Excision and skin grafting may be done.