Histology Of Bone

Histology Of Bone

“What is the histology of bone? A detailed question and answers guide”

Histology of Bone
Answer:

• It is a modified connective tissue
• It consists of Bone cells
• Histology of bone They are:
  1. Osteocytes
     • They are widely separated by Intercellular substance
     • This Intercellular substance consists of ground substance composed of Collagen fibres & mineral salts
     • They lie in lacunae
     • Contains eosinophilic cytoplasm
     • It decreases with age
       Functions:
     • Maintain the integrity of the lacunae & canaliculi
     • Help in removal or deposition of matrix & calcium
  2. Osteoblasts
     • These are bone forming cells
     • They are present lining growing surfaces of bone
     • There are numerous gaps between adjacent cells
     • Nucleus is ovoid & euchromatic
     • Cytoplasm is basophilic
       Functions:
     • Lay down organic matrix of bone
     • Responsible for calcification of the matrix
     • Help to shed off matrix vesicles
     • Inhibit or stimulate Osteoclasts
  3. Osteoclasts
     • They are bone resorbing cells
     • They are present over the resorptive surface of bone
     • They occupy bays called lacunae of Howship
     • They have numerous nuclei
     • They are derived from monocytes of blood
  4. Osteoprogenitor cells
     • They are precursor of osteoblasts & osteoclasts
     • They resembles fibroblasts in appearance
     • In fetus it is present at the site of bone formation
     • In adults present over bone surfaces
  5. Bone lining cells
     • They form a continuous epithelium like layer on bony surfaces They are flattened cells
     • They are present on both periosteal & endosteal surfaces

“Understanding the histology of bone through FAQs: Composition, functions, and uses explained”

Histology of bone Classification:

1. Lamellar bone
2. Woven bone
3. Compact bone
4. Cancellous bone

“Importance of studying the histology of bone for medical students: Questions explained”