Granulomatous Lesions

Granulomatous Lesions

Question 1. Write a short note on granulomatous lesions.
Answer:

Classification of granulomatous lesions or diseases

Specific or Infective Type

• Bacterial
  • Tuberculosis
  • Leprosy
  • Syphilis
  • Granuloma inguinale
  • Brucellosis
  • Cat scratch disease
  • Tularemia
  • Glanders
  • Actinomycosis.
• Fungal
  • Blastomycosis
  • Cryptococcosis
  • Coccidioidomycosis
  • Histoplasmosis
  • Parasitic
  • Schistosomiasis.

Granulomatous inflammation

• Non­-Specific
  • Sarcoidosis
  • Crohn’s disease
  • Silicosis
  • Berylliosis
  • Foreign body granuloma
  • Orofacial granulomatosis.

Question 2. Define inflammation. Give causes.
Answer:

Causes inflammation

1. Physical agents: Heat, cold, radiation, and mechanical trauma.
2. Chemical agents: Organic and inorganic poisons
3. Infective agents: Bacteria, virus, and their toxins
4. Immunological agents: Cell-mediated and antigen-antibody reactions.