Globulomaxillary Cyst: Evolution of Concepts and Current Understanding

Globulomaxillary Cyst: Evolution of Concepts and Current Understanding

Question. Write note on globulomaxillary cyst.

Answer. As per the older concept, globulomaxillary cyst was a visual cyst that arose from epithelium entrapped during fusion of the globular portion of the medial nasal process with the maxillary process.

“Understanding the role of globulomaxillary cysts in oral pathology: Q&A explained”

• As per the recent concept globular portion of the medial nasal process is primarily united with the maxillary process and fusion does not occur.
  Therefore, epithelial entrapment should not occur during embryologic development of this area.
• All cysts in the globulomaxillary region, i.e. between the lateral incisor and canine teeth can be explained on an odontogenic basis.
• Many are lined by inflmed stratifid squamous epithelium and are consistent with periapical cysts

“Importance of studying globulomaxillary cysts for better diagnostic outcomes: Questions explained”

• It was also theorized that some of these lesions may arise from inflmmation of the reduced enamel epithelium at the time of eruption of the teeth.
• In some cases cysts in the globulomaxillary area may be lined by pseudostratifid, ciliated, columnar epithelium. Such cases provide credence to the fisural theory of origin.
• Since fisural cyst in this region probably does not exist, the term globulomaxillary cyst should no longer be used.
• When a radiolucency between the maxillary lateral incisor and canine is encountered, the clinician should fist consider an odontogenic origin for the lesion.