Folic Acid

Folic Acid

Question 1. Give an account of the chemistry, sources, and dietary functions of folic acid.
Answer:

Folic acid:

Chemistry

• Consists of
• Pteridine ring
• p-amino benzoic ring (PABA)
• Glutamic acid
• Has one glutamic acid residue known as pleural-glutamic acid
• The active form is tetrahydrofolate
• Dihydrofolate reductase → folic acid → tetrahydrofolate
• H+ atoms are present at position 5,6,7 & 8 of tetrahydrofolate

“Understanding folic acid through FAQs: Functions, sources, and uses explained”

Sources

• Found in abundant in leafy vegetables

Dietary functions

• Involved in the synthesis of 1 C metabolism like
• Purine
• Pyrimidine nucleotide
• Glycine, serine, ethanolamine, choline
• N – formylmethionine

“Importance of studying folic acid for medical students: Questions explained”

Question 2. Write coenzyme form, one function, and one deficiency disorder of the following

1. Thiamine
2. Niacin
3. Ascorbic acid
4. Folic acid
5. Riboflavin
   

What is folic acid

Answer:

“Differential applications of traditional vs modern teaching tools: Questions answered”

“Common challenges in mastering folic acid notes effectively: FAQs provided”

Question 3. Describe the functions of thiamine
Answer:

Functions of Thiamine:

• Thiamine pyrophosphatase, TPP, a Coenzyme of Thiamine is required in the transmission of nerve impulse
• It is required for following enzyme activity
  • Pyruvate dehydrogenase to convert pyruvate to acetyl CoA
  • Alpha-ketoglutarate dehydrogenase
    • Used in the TCA cycle

“Factors influencing success with folic acid studies: Q&A”

Transketolase

• • Utilized in hexose monophosphate shunt
• Branches chain alpha-keto acid dehydrogenase
  • Used to catalyze the oxidative decarboxylation of branched-chain amino acids