Fibrous Dysplasia: Clinical Forms, Histology, and Surgical Management

Fibrous Dysplasia: Clinical Forms, Histology, and Surgical Management

Question. Write a note on firous dysplasia.
Or
Write a short note on firous dysplasia.

fibrous dysplasia treatment

Answer. Fibrous dysplasia is an idiopathic condition in which an area of normal bone is gradually replaced by abnormal fibrous connective tissue which then again undergoes osseous metaplasia and eventually the bone is transformed into dense lamellar bone.

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Types Of Fibrous Dysplasia

• Monostotic fibrous dysplasia: Only one of the bone is involved.
• Polyostotic fibrous dysplasia: More than one bone is involved.
  • Jaff’s type: Variable number of bones are involved accompanied by pigmented lesions of skin or cafe­aulait spots.
  • Albright syndrome: It is a severe form of fibrous dysplasia involving all the bones in the body, accompanied by pigmented lesions of the skin and endocrine disturbances of various types.

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Clinical Features Of Fibrous Dysplasia

• It is seen during the fist and second decades of life.
• Disease is more common among the females
• Polyostotic firous dysplasia commonly involve skull,facial bone, clavicle, pelvic bone, etc. and monostotic firous dysplasia involve maxilla and mandible.
• Monostotic form of disease can never be transformed into polyostotic form.

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Histopathology Of Fibrous Dysplasia

• Fibrous dysplasia reveals presence of highly cellular, proliferating well vascularized fibrillar connective tissue which replaces the normal bone.
• Within fibrous tissue the firoblasts cells are arranged in “Whorled pattern”.
• Trabeculae represent the Chinese lettr pattrn.
• Osteoblastic and osteoclastic activity may be present in relation to some trabeculae of bone.

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Treatment Of Fibrous Dysplasia

Surgical removal of lesion.