Differences Between Necrosis And Gangrene

Differences Between Necrosis And Gangrene

Question 1. Classify Necrosis. Give Differences Between Necrosis And Gangrene.
Answer:

Classification of Necrosis

• Coagulative Necrosis
• Liquefaction Necrosis
• Caseous Necrosis
• Fat Necrosis
• Fibrinoid Necrosis.

Difference between necrosis and gangrene

Differences Between Necrosis And Gangrene

Question 2. Define Necrosis And Enumerate The Causes Of Necrosis. Write The  Pathogenesis Of Caseous Necrosis.
Answer:

Necrosis is defined as focal death along with the degradation of tissue by hydrolytic enzymes liberated by cells.

Causes Of Necrosis

• Hypoxia
• Physical agents: Physical agents include mechanical trauma, extremes of temperature (burns and deep cold), sudden changes in atmospheric pressure, radiation, and electric shock.
• Chemicals and drugs: Trace amounts of agents known as poisons, such as arsenic, cyanide, or mercuric salts, may destroy sufficient numbers of cells within minutes to hours to cause death.
• Microbial agents: Injuries by microbes include infections caused by bacteria, rickettsiae, viruses, fungi, protozoa, metazoa, and other parasites.
• Immunologic agents: Hypersensitivity reactions, anaphylactic reactions, and autoimmune diseases.

Types of necrosis and gangrene

Pathogenesis Of Caseous Necrosis

Caseous necrosis is seen in tuberculosis. The development of caseous necrosis is possibly due to the interaction of mycobacteria with activated T cells as well as by the direct toxicity of mycobacteria on macrophages.