Classification of Proteins: Structure, Function, and Nutritional Value Explained
Classification of proteins.
Answer.
Definition Of Proteins
Proteins are polymers of amino acids.
They are the fundamental structural components of the body
Classification Of Proteins
Proteins can be classified in four ways
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- Classification based on shape and size
- Functional classification
- Classification based on chemical nature and solubility
- Nutritional classification
Classification based on Shape and Size
Classification of proteins
Based on shape and size, proteins are classified into 2 types – fibrous and globular
Fibrous Proteins
When the axial ratio of length to width of a protein molecule is more than 10, it is called a fibrous protein eg, keratin and collagen
Globular Proteins
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When the axial ratio of length to width of a protein molecule is less than 10, it is called a globular protein eg, haemoglobin and ribonuclease
Functional Classification Of Proteins
Based on the functions they perform, proteins are classified as
- Structural proteins – they are involved in the formation of structures of the body e.g. – keratin of hair and nail and collagen of bone
- Enzyme proteins – all enzymes are protein in nature, e.g., hexokinase, pepsin
- Transport proteins – proteins involved in the transport of substances,e.g. –
- Haemoglobin transports oxygen
- Albumin transports bilirubin
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- Hormonal proteins- some of the hormones are protein in nature, e.g., Insulin and growth hormone
- Contractile proteins – proteins that take part in muscle contraction. e.g. – Actin and myosin
- Storage proteins – proteins involved in the storage of substances, e.g., Ferritin stores iron
- Genetic proteins – proteins involved in genetic function e.g., Nucleoprotein
- Defence proteins – proteins involved in defence function, e.g., Immunoglobulins
- Receptor proteins – proteins that act as receptors e.g. – Cytokine receptor, integrin
- Respiratory proteins – proteins involved in the function of respiration e.g. – Haemoglobin and cytochrome
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Classification Based On Chemical Nature And Solubility
According to this proteins are classified into 3 groups – simple, conjugated and derived
Simple Proteins
These are proteins that on complete hydrolysis ,yield only amino acids.
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Example:
- Protamine – they are small molecules rich in arginine
- Histones – they are found in association with DNA
- Albumin – normal serum level is 3.5 to 5 gm %
- Globulin – normal serum level is 1.8 to 3.6 gm %
- Gliadin – it is rich in proline
- Glutelin – it is rich in glutamic acid
- Scleroproteins – these proteins have great stability and very low solubility and form supporting structures in the body, e.g. –
- Keratin of hair
- Collagen of bone
- Elastin of connective tissue
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Proteins and their functions
Conjugated Proteins
- Conjugated proteins are simple proteins combined with a non-protein group called a prosthetic group
- The protein part is called apoprotein, and the entire molecule is called holoprotein
- E.g. nucleoprotein, mucoprotein, glycoprotein, chromoprotein, phosphoprotein, lipoprotein, and metalloprotein
Nutritional Classification Of Proteins
From the nutritional point of view, proteins are classified as
- Complete proteins
- Partially incomplete proteins
- Incomplete proteins
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Complete Proteins
These proteins have all the essential amino acids in the required proportions by the human body to promote good growth, e.g., egg albumin and milk casein
Complete and incomplete proteins Partially Incomplete Protein
These proteins are partially lacking one or more essential amino acids and hence can promote moderate growth, e.g., wheat and rice proteins (lack lysine and threonine)
Incomplete Proteins
These proteins completely lack one or more essential amino acids, hence do not promote growth at all, e.g., gelatin (lacks tryptophan), maize/corn (lacks tryptophan and lysine).
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