Cirrhosis of the Liver: Causes and Risk Factors

Cirrhosis of the Liver: Causes and Risk Factors

Question. Enumerate the causes of cirrhosis in liver.

Answer. Following are the causes of cirrhosis of liver:

1. Viral hepatitis B and C

2. Alcohol

3. Cryptogenic

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4. Metabolic:

• Hemochromatosis
• Wilson’s disease
• α1—antitrypsin defiiency
• Cystic firosis
• Glycogen storage disease
• Galactosemia

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5. Biliary obstruction:

• Primary biliary cirrhosis
• Sclerosing cholangitis
• Secondary biliary cirrhosis

6. Venous outflw obstruction:

• Budd­Chiari syndrome
• Veno­occlusive disease
• Congestive heart failure

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7. Drugs:

• Methotrexate
• Methyldopa
• Oxyphenisatin
• Amiodarone