Folinic Acid Write The Basis Of Folinic Acid Is Given With Chemotherapy For Cancer. Answer: Folinic acid is given with chemotherapy for cancer because the chemotherapeutic drugs especially methotrexate is a folate antagonist. It acts by inhibiting dihydrofolate reductase, blocking the conversion of dihydrofolic acid to tetrahydrofolic acid. So methotrexate is … [Read more...] about Folinic Acid
Pharmacology
Teratogenicity
Teratogenicity "What is teratogenicity and why is it important?" Teratogenic Drugs It refers to the capacity of a drug to cause fetal abnormalities when administered to the pregnant mother. The placenta does not strictly constitute a barrier and any drug can cross it to a greater or lesser extent. The embryo is one of the most dynamic biological systems and in … [Read more...] about Teratogenicity
Classification Of Adrenergic Drugs
Classification Of Adrenergic Drugs "What is the classification of adrenergic drugs?" Classification Of Adrenergic Drugs Based On Their Therapeutic Uses Pressor Agents: Noradrenaline, phenylephrine, ephedrine, dopamine, methoxamine, phentermine Cardiac Stimulants: Adrenaline, Dobutamine, Isoprenaline Bronchodilators: Isoprenaline, Salbutamol, Salmeterol, … [Read more...] about Classification Of Adrenergic Drugs
Uses And Adverse Effects Of Adrenaline
Uses And Adverse Effects Of Adrenaline "What are the uses and adverse effects of adrenaline?" Therapeutic Uses Of Adrenaline Anaphylactic shock: Adrenaline acts as a life-saving drug in anaphylactic shock and also in Type I hypersensitivity reaction. It should be given as 0.3 to 0.5 ml of 1:1000 solution and is given IM. Allergy: It reverses the manifestations of … [Read more...] about Uses And Adverse Effects Of Adrenaline
Pharmacological Actions Of Adrenaline
Pharmacological Actions Of Adrenaline "What are the pharmacological actions of adrenaline?" Dopamine is adrenergic alpha and beta 1 but not beta 2 agonist. In IV low-dose dopamine dilates the blood vessel and increases GFR and sodium secretion. At a normal dose, it increases the cardiac output and systolic blood pressure with little effect on diastolic blood pressure. It … [Read more...] about Pharmacological Actions Of Adrenaline