Pharmacology

Metyrapone Question 1. Write A Short Note On Metyrapone. Answer: Metyrapone is a glucocorticosteroid. Mechanism of action: It inhibits 11 β hydroxylases in the adrenal cortex and prevents hydrocortisone → increased ACTH release → increase excretion of 11. desoxycortisol in urine. In pituitary disease, urinary excretion of 11. desoxycortisol fails to increase in … [Read more...] about Metyrapone

Uses Of Corticosteroids Write Important Uses, Side Effects, And Contraindications Of Corticosteroids. Or Write Important Indications, Side Effects, And Contraindications Of Adrenocortical Steroids. Answer: Uses Of Corticosteroids 1. Endocrinal uses. Replacement therapy Acute adrenal insufficiency: Since it is a medical emergency that occurs due to infection … [Read more...] about Uses Of Corticosteroids

Effects Of Glucocorticoids Describe The Therapeutic Uses And Adverse Effects Of Glucocorticoids. Or Write In Brief On Uses And Adverse Effects Of Glucocorticoids. Answer: Uses Of Glucocorticoids 1. Endocrinal uses. Replacement therapy Acute adrenal insufficiency: Since it is a medical emergency that occurs due to infection or due to sudden withdrawal of … [Read more...] about Effects Of Glucocorticoids

Reactions Of Corticosteroids Write Important Uses, Side Effects, And Contraindications, If Any, Of Glucocorticoids. Or Write Short Note On the Therapeutic Uses And Adverse Reactions Of Corticosteroids. Answer: Uses Of Corticosteroids 1. Endocrine uses. Replacement therapy Acute adrenal insufficiency: Since it is a medical emergency that occurs due to … [Read more...] about Reactions Of Corticosteroids

Heparin Question 1. Write Short Note On Heparin. Answer: Heparin is an anticoagulant drug that is used both in vivo and in vitro. Heparin Pharmacokinetics Heparin is given orally due to its high negative charge and large molecular size is not absorbed. It should be given IV or SC On given IV it immediately acts. It does not cross the blood-brain barrier or … [Read more...] about Heparin