Blood Urea, Creatinine, And Glucose: Normal Ranges Explained

Blood Urea, Creatinine, And Glucose: Normal Ranges Explained

Question 1. Vanderbegh test
Answer:

• Van den Bergh test is used to identify an increase in serum bilirubin

Reagent used:

• A mixture of an equal volume of sulfanilic acid in dilute HCl and sodium nitrate

Reactions:

• Direct reaction
  • Detects conjugated bilirubin
• Indirect reaction
  • Detects unconjugated bilirubin
• Biphasic
  • Useful when serum contains both conjugated and unconjugated bilirubin

Question 2. Briefly write on the urea clearance test
Answer:

• Urea is the end product of protein metabolism

Definition:

• It is defined as the volume of plasma that would completely clear of urea per min

Calculation:

\(C_m=\frac{U^* \mathrm{~V}}{\mathrm{P}}\)

Cm = Maximum urea clearance output of urine more than 2 ml/min U urea concentration in urine (mg/ml)

V urine excreted per min in ml

P = urea concentration in plasma (mg/ml)

Normal value:

75 ml/min

Significance:

• A value below 75% of normal indicates renal damage
• A value below 50% of normal indicates an increase in blood urea level

Question 3. Write normal values for
Answer:

• Blood urea, Random blood glucose, Serum creatinine
• Blood urea-10-40 mg/dl
• Random blood glucose 80-140 mg/dl
• Serum creatinine 0.6-1 mg/dl