Antitubercular Drugs Question And Answers

Antitubercular Drugs Question And Answers

Question 1. Write Different Groups Of Antitubercular Drugs. Discuss Important Toxic Manifestations Of Streptomycin With Important Therapeutic Uses.
Answer:

Those drugs which are given against tuberculosis are known as antitubercular drugs.

“Understanding the role of antitubercular drugs in treating tuberculosis”

Groups Of Antitubercular Agents

• First Line: These drugs have high antitubercular efficacy as well as low toxicity and are used routinely. The first line of drugs is isoniazid, streptomycin, rifampin, pyrazinamide, and ethambutol.
• Second Line: These drugs have low antitubercular efficacy or high toxicity or both and are used in special circumstances. The second line of drugs used are thiacetazone, para-aminosalicylic acid, ethionamide, cycloserine, kanamycin,amekacin, capeomycin.

“Techniques for managing high-risk groups with TB”

“Importance of studying antitubercular drugs for global health”

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Toxic Manifestations Of Streptomycin

• Streptomycin is avoided during pregnancy because if used in infants it causes fetal ototoxicity.
• It is avoided using other ototoxic drugs like minocycline and diuretics.
• It is avoided using nephrotoxic drugs like amphotericin B and cyclosporine.
• It should not be mixed with any other drug in the same syringe.

Antitubercular Drugs Therapeutic Uses

It is used in tuberculosis, plague, tularemia, brucellosis, urinary tract infections, and septicemias.

“Treatment options for tuberculosis requiring antitubercular drugs”

Question 2. Enumerate Primary Antitubercular Drugs.
Answer:

Enumeration of Primary Antitubercular Drugs

• Isoniazid
• Rifampicin
• Pyrazinamide
• Ethambutol
• Streptomycin.

“Role of Directly Observed Therapy (DOT) in managing TB”

Question 3. Enumerate Fist Line Antitubercular Drugs.
Answer:

Following are fist line antitubercular drugs:

• Isoniazid
• Rifampin
• Pyrazinamide
• Ethambutol
• Streptomycin.