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Home » Ampicillin

Ampicillin

October 5, 2025 by Kristensmith Taylor Leave a Comment

Ampicillin

Write A Note On Ampicillin.
Or
Discuss In Brief The Mechanism Of Action, Therapeutic Uses, And Adverse Affects Of Ampicillin.
Answer:

Ampicillin Mechanism Of Action

Following is the mechanism of action of ampicillin:

Amoxicillin Mechanism PBP_Inhibition Peptidoglycan Synthesis

Ampicillin Therapeutic Uses

  • In dentistry: Ampicillin and sulbactam combination is used in the treatment of L Ludwig’s angina.
  • Upper respiratory infections: Ampicillin is used for the treatment of pharyngitis, sinusitis, otitis media, etc. caused due to S. pyogenes, S. pneumoniae, and H. influenza.
  • Urinary tract infections: Ampicillin is used if the patient is sensitive to fluoroquinolones.
  • Meningitis:  A combination of ampicillin, vancomycin, and cephalosporin mainly third-generation is used to treat meningitis.
  • Bacillary dysentery: In some patients, ampicillin is used but most of the strains develop resistance to it.
  • Typhoid fever: Ampicillin is indicated to remove the carrier state of the microorganism.

Ampicillin Adverse Effects

  • Diarrhea is common after oral administration.
  • Hypersensitivity reaction i.e. skin rashes.
  • Pain at the site of IM injection.

Filed Under: Pharmacology

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