Acid Phosphatases
“What are acid phosphatases? A detailed question and answers guide”
Acid phosphatase.
Answer:
- Importance
- Related to the transfer of phosphate esters in the organic matrix of bone, enamel and dentin.
- Related to resorption of bone and dentin.
- Reflects metabolic activity of different oral tissues.
- Associated with the hydrolysis of carboxylic acid esters of alcohol Involved in the formation of cAMP.
- It is localized in membrane-bound vesicles called lysosomes.
- Types: Based on its interaction with substrates
- Para-nitro-phenyl phosphate
- Beta glycerophosphate.
“Importance of studying acid phosphatases for biochemistry students: Questions explained”
What is acid phosphatase
Activity:
- In supranuclear and distal regions of secretory ameloblasts.
- During resorption, osteoclasts of bone and odontoblasts in resorbing dentin.
- Less activity occurs during the late secretory stage of amelogenesis.
“Understanding acid phosphatases through FAQs: Functions, classification, and uses explained”
Demonstration:
- Demonstrated cytochemical using naphthol ASBI phosphoric acid-fast red garnet GBC.
- In tissue sections using naphthol ASBI phosphoric acid pararosaniline.
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