Mucosal Candidiasis Clinical Presentation

Mucosal Candidiasis Clinical Presentation

Question. Write a short note on acute pseudomembranous candidiasis.
Or
Write a short note on oral thrush.

“Understanding the clinical presentation of mucosal candidiasis: Q&A explained”

Answer. It is commonly known as “oral thrush”.

• Acute pseudomembranous candidiasis appears as a smooth, thick, creamy­white or allow, soft and friable plaque on the oral mucosa.
• Plaque can be easily wiped of by gentle scraping, which leaves an erythematous, raw, bleeding surface in the underlying area.
• Lesions may occur at any mucosal site and vary in size ranging from small areas to confluent plaques.
• Plaque consists of fungal organisms, keratotic debris, inflammatory cells, desquamated epithelial cells, and firin, etc.
• Oral thrush commonly occurs among children, debilitated elderly persons and AIDS patients.

“Importance of recognizing mucosal candidiasis clinical features: Questions explained”

Histopathology

• Hyperplastic epithelium with superficial necrotic and desquamating parakeratinized layer.
• Hyperplastic epithelium is infiltrated by candidal hyphae and yeast cells along with PMNs.
• Often, there is a separation between the superficial pseudomembrane and the deeper layers of epithelium.
• Candidal hyphae often appear as a weakly basophilic, thread-like structures.
• Lamina propria is infiltrated by chronic inflammatory cells,i.e., lymphocytes and plasma cells.

“Common challenges in diagnosing mucosal candidiasis effectively: FAQs provided”

“Steps to explain causes of mucosal candidiasis: Candida albicans vs immune suppression: Q&A guide”

Treatment

• Anti­fungal drugs, i.e., nystatin, amphotericin­B should be given.
• Proper oral hygiene should be maintained.