Adverse Effects Of Propranolol
Question 1. Write In Brief Antihypertensives Of Choice For Treatment Of High Blood Pressure, Detected Just Before Dental Procedure.
Answer:
Following are the antihypertensives of choice for the treatment of high blood pressure detected just before a dental procedure:
- Enalapril 2.5 to 40 mg OD orally.
Or - Lisinopril 5 to 40 mg OD orally.
Or - Ramipril 1.25 to 20 mg OD orally.
Or - Losartan 25 to 50 mg OD or BD orally.
Or - Propranolol 10 to 120 mg 2 to 4 times a day orally.
Or - Atenolol 25 to 100 mg OD orally.
Or - Amlodipine 2.5 to 10 mg OD orally.
Question 2. Enumerate Adverse Effects Of Propranolol.
Answer:
The following are the adverse effects of propranolol:
- Propranolol can accentuate myocardial insufficiency and worsen congestive heart failure.
- Bradycardia
- Propranolol worsens chronic obstructive lung disease and can precipitate bronchial asthma.
- Propranolol exacerbates variant angina due to unopposed mediated coronary constriction.
- Carbohydrate tolerance may be impaired in prediabetics.
- Plasma lipid profile is altered on long-term usage.
- If the gradual withdrawal of propranolol is not done after long-term use, it leads to rebound hypertension, worsening of angina, and sudden death.
- Tiredness and reduced exercise capacity.
- Cold hands and feet.
- GIT upset, lack of sexual drive, nightmares, forgetfulness, male patients have sexual distress.
Question 3. Classify And Enumerate Fist Line Antihypertensive Drugs.
Ans.
Following are the fist line antihypertensive drugs:
- Thiazide diuretics: Hydrochlorothiazide, chlorthalidone, indapamide
- Angiotensin II receptor blockers (ARBs): Losartan, candesartan, irbesartan, valsartan, telmisartan
- ACE inhibitors: Captopril, enalapril, lisinopril, perindopril, ramipril, fosinopril
- Calcium channel blockers: Verapamil, diltiazem, nifedipine, felodipine, amlodipine, nitrendipine, lacidipine
- Beta adrenergic blockers: Propranolol, metoprolol, atenolol.
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