Understanding Purpura and Its Oral Clues

Understanding Purpura and Its Oral Clues

Question 1. Write notes on purpura.

Answer. It is defined as a purplish discoloration of skin and mucous membranes due to subcutaneous and submucosal extravasation of blood.

Clinical Features

“Common challenges in diagnosing purpura effectively: FAQs provided”

• Purpura commonly occurs among adults below 40 years, and females are more commonly affected.
• Sudden spontaneous occurrence of petechiae (small pinpoint hemorrhages under skin or mucosa), ecchymoses or hematomas in skin and mucous membrane.
• Bleeding spots on the skin or mucosal surface that do not blanch on pressure.
• Women may have heavy menses or bleeding between periods.
• Spontaneous gingival bleeding is present.
• Bleeding into the TMJ results in pain and trismus.

“Understanding purpura through FAQs: Q&A explained”

Treatment

• Steroid therapy and repeated blood transfusions.
• Splenectomy and immunosuppressive drug therapy is required.

“Importance of studying purpura for better diagnostic outcomes: Questions explained”

Question 2. Write a short note on oral manifestations of leukemia.

Answer. The following are the oral manifestations of leukemia Patient has got gingival hyperplasia, which is a constant feature of leukemia.

• Gingiva becomes boggy, edematous, and deep red, and bleeds easily.
• Gingival swelling is present due to leukemic infiltration.
• Purpuric lesions of the oral mucosa, analogous to cutaneous ecchymosis, may also be seen.
• Loosening of teeth due to necrosis of the PDL is present.
• Destruction of the alveolar bone is seen.
• Crusting of lips is also seen.