Dentigerous and Epidermoid Cysts: Pathogenesis, Features & Malignant Potential

Dentigerous and Epidermoid Cysts: Pathogenesis, Features & Malignant Potential

Question 1. Classify the cysts of the jaw. Describe the pathogenesis, histopathology and clinical features, and malignant potential of dentigerous cyst.

Answer.

“Role of odontogenic epithelium in causing dentigerous cysts: Questions answered”

Malignant Potential of Dentigerous Cyst

• Malignant potential of the epithelium of dentigerous cysts to ameloblastoma, epidermoid carcinoma and mucoepidermoid carcinoma.
• Development of ameloblastoma is from rest of the odontogenic epithelium or lining epithelium of cyst is known as mural ameloblastoma.
• Mucoepidermoid carcinoma is the malignancy of salivary gland. The mucoepidermoid carcinoma is usually associated with lining epithelium of dentigerous cyst or dentigerous cyst which consist of mucous secreting cell.
• Epidermoid carcinoma can also develop from dentigerous cyst from rest of the odontogenic epithelium or lining of epithelium of cyst.

“Understanding the role of dentigerous cysts in oral pathology: Q&A explained”

Question 2. Write note on epidermoid cyst.

Answer. It is also called epidermoid inclusion cyst or epidermoid cyst or keratin cyst or sebaceous cyst.

• Epidermoid inclusion cysts are the result of implantation of epidermoid elements and its subsequent cystic transformation.

Clinical Features Of Epidermoid Cyst

• It is most common in 3rd and 4th decades of life.
• It is twice as common in men as in women.
• Common sites are face, trunk, neck extremities and scalp.
• Epidermoid cyst appears as fim, round, mobile, flsh colored to yellow or white subcutaneous nodules of variable size. In some patients, it contains melanin pigments.
• Discharge of foul smelling cheese like material is a common complaint.
• Sometimes cyst becomes inflmed and infected resulting in pain and tenderness.
• When located orally, it can cause diffilty in feeding,swallowing and even speaking.

“Importance of studying cyst pathogenesis for better diagnostic outcomes: Questions explained”

Histological Features Of Epidermoid Cyst

• Cyst is lined by the stratifid squamous epithelium with glandular diffrentiation.
• Cyst is filed with desquamated keratin disposed in a lamellar pattrn.
• Dystrophic calcifiation and reactive foreign body reaction are seen associated with the cystic capsule.
• Pigmented epidermoid cyst may demonstrate melanin pigment in the wall and a keratin may present.
• A surrounding infitrate of melanocytes and macrophages may be observed.

“Common challenges in diagnosing dentigerous and epidermoid cysts effectively: FAQs provided”

Treatment Of Epidermoid Cyst
Surgical excision is done.