Histopathology of Ewing’s Sarcoma: Cellular and Vascular Features

Histopathology of Ewing’s Sarcoma: Cellular and Vascular Features

Question. Write a short note on Ewing’s sarcoma—histopathology.

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Answer. Following is the histopathology of Ewing’s sarcoma:

Ewing’s sarcoma pathology slides

• The lesion consists of solid sheets of small round cells with very minimal stroma but at a few places, connective tissue septae are present.
• Cells are round and small in shape along with scanty cytoplasm, nuclei of the cell is large,e round to oval in shape along with dispersed chromatin and hyperchromasia.
• Borders of cell are ill defied.
• Cells also show mitotic fiures.
• Cells of the sarcoma are arranged in fiigree pattrn.
• Small vascular channels are also evident.
• Hemorrhage along with vascular lakes or sinuses are appreciated.
• Perivascular sparing and geographical necrosis is very common in Ewing’s sarcoma.

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