Central Giant-Cell Granuloma

Central Giant-Cell Granuloma

Question. Write a short note on central giant cell granuloma.
Answer. Central giant cell granuloma is a fibro-osseous lesion of the jaw.

Central giant-cell granuloma mandible

Central Giant Cell Granuloma Types

• Non-aggressive: This shows slow growth and has benign behavior.
•  Aggressive: It shows rapid growth and is a destructive lesion.

For clinical features, radiographic features, and differential diagnosis, 7 of the same chapter.

Central Giant Cell Granuloma Diagnosis

• Clinical diagnosis: Presence of expansile swelling in the anterior region of the mandible.
• Radiological diagnosis: Radiolucency crossing the midline is suggestive of central giant cell granuloma
• Laboratory diagnosis: The biopsy shows multinuclear giant cells and loose fibrillar connective tissue stroma.

Central giant-cell granuloma

Central Giant Cell Granuloma Management

• Curettage of the lesion should be done thoroughly.
• Weekly injection of corticosteroids, i.e., triamcinolone acetonide, is directly injected into the tumor.
• Administration of salmon calcitonin may lead to the resolution of the lesion. This is given daily for a year as an intradermal injection or a nasal spray.
• Partial resection of an aggressive tumor can be done