Fatty Liver And Cholesterol: Causes, Effects, And Metabolic Insights

Fatty Liver And Cholesterol: Causes, Effects, And Metabolic Insights

Question 1. Cholesterol.
Answer:

• It is exclusively found in animals.
• Widely distributed in all cells.

Structure:

• C₂7H₄₆ O.
• It has

1. One hydroxyl group at Cg
2. The double bond between C₅ and C₅.
3. 8 carbon aliphatic side chain attached to
4. Contains a total of 5 methyl groups.

Properties:

• Weakly amphiphilic.
• Yellowish crystalline solid.
• Microscopically appears notched-shaped.
• Insoluble in water.
• Soluble in organic solvents.

Question 2. Fatty liver.
Answer:

• Accumulation of excessive lipids in the liver results in fatty liver.

Features:

• The appearance of droplets of triacylglycerols in entire cytoplasm of hepatic cells.
• Impaired metabolic functions of the liver.
• Cirrhosis of the liver.

Causes:

• Increased synthesis of triacylglycerols.
• Impairment in lipoprotein synthesis.