Packed Cell Volume Test
Question 1. Packed cell volume (PCV).
Answer:
Definition:
- It is the volume of RBCs packed at the bottom of a haemotocrit tube when the blood is centrifuged.
- It is expressed as the percentage of cellular elements with that of whole blood.
Significance:
- PCV helps in.
- Diagnosis and treatment of anaemia and polycythemia.
- Determine the extent of dehydration.
- Determine the need for blood transfusion.
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Normal values:
- In males – 40-45%.
- In females – 38-42%.
Question 2. Define Hemolysis and fragility. (or) Himophilia. (or) Purpura.
Answer:
Hemolysis:
- It is the process which involves the breakdown of RBC and liberation of haemoglobin.
Fragility:
- The susceptibility of RBC to hemolysis or tendency to break easily is called fragility.
- It has two types.
- Osmotic fragility due to exposure to hypotonic saline.
- Mechanical fragility – due to mechanical trauma.
“Importance of studying the packed cell volume test for medical students: Questions explained”
Question 3. Leukocytes.
Answer:
- They are the colourless and nucleated formed elements of blood.
- They are large than RBC
Classification:
1. Granulocytes:
- Neutrophils.
- Eosinophils.
- Basophils.
2. Agronulocytes:
- Monocytes.
- Lymphocytes.
Normal count:
- At birth -20,000/mL.
- In adults – 4,000-11,000/mL
Life-span:
- It is varies from half a day to 3-6 months.
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Properties:
1. Diapedesis – squeezing of WBC through blood vessels.
2. Ameboid movement.
- WBC change their shape by protruding into the cytoplasm.
3. Chemotaxis.
- Attracted by the chemical substances present in the tissues.
“Factors influencing success with packed cell volume test studies: Q&A”
4. Phagocytosis.
- Engulf foreign body and destroy them.
Functions:
- They play an important role in defence mechanism.
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