Metabolic Changes In Diabetes Mellitus

Metabolic Changes In Diabetes Mellitus

Question 1. Metabolic changes in diabetes mellitus
Answer:

• Diabetes mellitus is associated with several metabolic alterations
• The most important of them are:

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↓Glucose uptake
↑Glucose production

Major Metabolic Changes In Diabetes Mellitus:

Absolute or relative insulin deficiency
↓
Multiple metabolic effects
↓

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Question 2. GTT.
Answer:

• It means a glucose tolerance test.
• The diagnosis of diabetes is made on the basis, of individuals’ response to the oral glucose load n n-her-d as an oral glucose tolerance test.

Value:

1. In normal individuals.

• Fasting glucose concentration – 75 – 110 mg/dl.

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2. In patients with impaired glucose tolerance.

• Fasting glucose – 110 – 26 mg/dl.
• Postpardinal glucose – 140 – 200 mg/dl.

3. In diabetic patients.

• Fasting glucose – exceeds 126 mg/dl.
• Postpardinal glucose – exceeds 200 mg/dl.

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