Glucose Tolerance Test
Oral glucose tolerance test.
Answer:
Definition:
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The diagnosis of diabetes made on the basis of individuals’ response to the oral glucose load is called the glucose tolerance test (GTT).
Preparation of the subject:
- The subject is provided with a carbohydrate-rich diet for at least 3 days prior to the test.
- Drugs affecting carbohydrate metabolism are discontinued for at least 2 days.
- Strenuous exercise and smoking should be avoided on the previous day of the test.
- The subject should be in an overnight fasting state.
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Procedure:
- Conducted preferably in the morning.
- Fasting blood and urine sample is taken.
- Next, the subject is given 75 g of glucose dissolved in about 300 ml of water, given orally.
- Blood and urine samples are collected at the interval of 30 minutes for 2 hours.
- The values obtained are plotted on a graph.
Interpretation:

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