Vitamin B12

Vitamin B12

“What is Vitamin B12? A detailed question and answers guide”

Question 1. Vitamin B12.
Answer:

It is cyanocobalamine

Coenzyme forms:

• 5′- Deoxyadenosyl cobalamin
• Methylcobalamin

Functions:

1. Synthesis of methionine from homocysteine
   • Vitamin B12 is used as Methylcobalamin in this reaction
2. Isomerization of methylmalonic CoA to succinyl CoA
   • It occurs in the presence of vitamin B12 Coenzyme, deoxyadenosine cobalamin

“Understanding Vitamin B12 through FAQs: Composition, functions, and uses explained”

Dietary requirements:

• Adults- 3 micrograms/ day
• Children-0.5-1.5 microgram/day
• During pregnancy & lactation- 4 micrograms/ day

Deficiency symptoms:

• A deficiency of vitamin B12 leads to
• Pernicious anemia
• characterized by low hemoglobin levels, decreased number of erythrocytes & neurological manifestations
• Neuronal degeneration
• Demyelination of the nervous system

“Importance of studying Vitamin B12 for medical students: Questions explained”

Question 2. Riboflavin deficiency 
Answer:

1. Riboflavin deficiency symptoms include
   1. Cheilosis
      • Presence of fissures at the comer of the mouth
   2. Glossitis
      • Tongue appears smooth & purplish
   3. Dermatitis