Vitamin C Deficiency
Give an account of the sources, metabolic functions, daily requirements & deficiency manifestation of vitamin C.
Answer:
Vitamin C:
Sources:
- Citrus fruits- Gooseberry, guava
- Green vegetables
- Tomatoes & Potatoes
Functions:
1. Role in collagen formation
- It acts as a coenzyme in the hydroxylation of proline & lysine
- These are required to convert procollagen to collagen
2. It is required for bone formation
3. Role in metabolism
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- Iron metabolism
- It enhances iron absorption
- Helps in tire formation of ferritin
- Helps in the mobilization of iron from ferritin
- Hemoglobin metabolism
- It is used to reconvert methemoglobin to hemoglobin
- Required for degradation of hemoglobin to bile pigments
- Tryptophan metabolism
- Essential for hydroxylation of Trytophan to hydroxytryptophan
- Tyrosine metabolism
- Required for oxidation of p-hydroxy phenylpyruvate to homogentisate acid
- Polic acid metabolism
- Required for the formation of tetrahydrofolate, an active form of folic acid
“Importance of studying Vitamin C deficiency for medical students: Questions explained”
4. Hormonal functions
- Peptides are derived from glycine
- Vitamin C is required for the hydroxylation of glycine
- It is required for the synthesis of steroids hormones
- It is a strong antioxidant
5. It enhances the synthesis of immunoglobulin
6. Preventive functions
7. It prevents the risk of
- Cataract
- Cancer
- Coronary heart diseases
“Factors influencing success with Vitamin C deficiency studies: Q&A”
Daily requirements:
- The daily requirement of vitamin C is 60-70 mg
Deficiency manifestations:
- A deficiency of vitamin C leads to scurvy
Features of scurvy:
- Spongy & sore gums
- Loose teeth n Anemia
- Swollen joints
- Fragile blood vessels
- Decreased immunocompetence
- Delayed wound healing
- Impaired hormonal functions of adrenal cortex & gonads B Hemorrhage
- Osteoporosis
“Common challenges in mastering Vitamin C deficiency notes effectively: FAQs provided”
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