Wound Healing And Growth Factors

Wound Healing And Growth Factors

Oral cavity contains more than 100 types of microorganisms still oral wounds heal as fast as any other wound in body. Justify.
Answer. The rapid healing in oral mucosa is directly related to intrinsic characteristics of the oral tissue and not to environmental such as microflora.

• Oral epithelium has large amount of palmitic acid (16:0) due to which there is a high energy metabolism in the oral mucosa.
• In the oral cavity, saliva provides many essential growth factors, making macrophage function less critical. Saliva has large amounts of cytokines, growth factors, and protease inhibitors which are the primary factors that account for rapid oral wound healing.
• Microorganisms in the oral cavity stimulate wound healing.
• Wounds of oral mucosa were shown to contain significantly lower levels of macrophages, neutrophils and T-cells when compared with wounds of any other part of body.